The Science Behind Bone Glue: A Game-Changer in Medicine

Bone glue, also known as bone adhesive or bone cement, is a surgical adhesive used to reinforce or replace screws, plates and pins for fixation of bone fractures. It is a viscous liquid synthetic polymer that is injected or brushed onto fractured bone pieces to fuse them together. Bone glue provides immediate fixation of bone segments and allows early mobilization. It is less invasive compared to metal plates and screws as it does not require incisions for implant insertion. Being bioabsorbable, bone glue dissolves gradually and gets replaced by the patient's own bone, thus avoiding a second surgery for implant removal. It causes minimal damage to bone and soft tissues during application.
Global Bone Glue Market is estimated to be valued at USD 3.08 Bn in 2025 and is expected to reach USD 4.60 Bn by 2032, exhibiting a compound annual growth rate (CAGR) of 5.9% from 2025 to 2032.
Key Takeaways
Key players operating in the bone glue market are Baxter International, CryoLife Inc., Luna Innovations Incorporated, B. Braun Melsungen AG, Johnson & Johnson, Cohera Medical, Inc., Tissuemed Ltd., C.R. Bard Inc., DENTSPLY SIRONA Inc., Chemence Medical, Inc.
The increasing prevalence of sports injuries and road accidents globally is generating higher demand for bone glue for fast healing of fractures without hardware implantation. According to the NIH, nearly 1.7 million road accidents occur in India every year causing 2,00,000 orthopedic injuries annually.
Advanced Bone Glue Market Opportunities made of calcium phosphate are exhibiting osteoconductive properties promoting faster bone regeneration compared to traditional bone adhesives. Companies are focusing on developing bone glues that can be easily applied to irregular fracture surfaces and achieve sufficient bonding strength in few minutes.
Market Trends
- Bone glues are increasingly replacing the use of metal plates and screws in pediatric fractures and joint fractures near articular surfaces due to their minimal invasiveness.
- Development of antibacterial bone glues incorporating silver nanoparticles or antibiotics is a key trend to prevent post-operative infections in fracture fixation.
Market Opportunities
- Rising number of trauma and accident cases in developing nations offers significant growth opportunities for bone glue producers aiming to enter new markets.
- Market potential exists for development of 3D printable, customized bone glue implants matching the geometry of irregular bone defects caused by tumors or non-union fractures.
Bone Glue Market Impact of COVID-19
The COVID-19 pandemic has impacted the bone glue market in both negative and positive ways. Initially during the lockdowns imposed globally, elective surgeries were postponed which led to reduced demand for bone glues. However, as the number of accidents and trauma cases increased due to non-availability of hospitals, the need for bone glue in emergency situations rose dramatically. Many regions also witnessed a surge in the number of fractures among elderly populations living alone due to fall injuries at home during lockdowns.
As restrictions have eased now in most parts of the world, elective surgeries have resumed. However, supply chain disruptions caused by lockdowns impacted the availability of raw materials required for manufacturing bone glues. This led to short term price increases and supply shortages. Companies have now ramped up production and streamlined logistics to meet the increasing post COVID demand. The pandemic has also boosted research innovation in the field, with many companies developing bone glues that can set faster and work better in infection-prone conditions. It is estimated that demand will continue growing above pre-COVID levels in the forecast period as usage of bone glues becomes more widespread.
Geographical Regions of Bone Glue Market in Terms of Value
North America accounts for the largest share of the global bone glue market in terms of value, led by the United States. This is attributed to factors such as the large healthcare expenditure, rising incidence of trauma injuries, growing elderly population undergoing orthopedic surgeries, and rapid adoption of advanced medical technologies in the region. Within the US, states such as California, Texas and New York generate the highest demand for bone glues due to their large populations and higher disposable incomes levels.
Fastest Growing Region for Bone Glue Market
Asia Pacific region is expected to witness the fastest growth in the bone glue market during the forecast period. This can be attributed to rising healthcare infrastructure, growing medical tourism industry in countries like India and Thailand, large patient pools in densely populated nations such as China and India, and increasing government focus on making quality healthcare more accessible and affordable in the region. Additionally, growing prevalence of osteoporosis among aging populations, rising standards of living and greater product affordability will further aid the high growth trajectory of the Asia Pacific bone glue market in the coming years.

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About Author:

Money Singh is a seasoned content writer with over four years of experience in the market research sector. Her expertise spans various industries, including food and beverages, biotechnology, chemical and materials, defense and aerospace, consumer goods, etc. (https://www.linkedin.com/in/money-singh-590844163)


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